CapBuild is an easy-to-use web tool that lets anyone -- from a student to an advanced scientist -- design, modify, and visualize AAV capsids right in their web browser: You don’t need to install anything. You don’t need to learn any coding. All you need is an internet connection and an idea.

Gene therapy is changing the way we treat diseases.  These new therapies target and correct the underlying issue in the patient’s DNA. This is done by delivering a therapeutic cargo (typically a DNA or RNA sequence) into the cell using viral capsids, protein shells derived from common viruses. These viral shells, especially those made from adeno-associated viruses (or AAVs), need to be carefully designed so they can carry genetic material safely and effectively to the right place in the body.

Value Proposition

Instant Capsid Assembly
CapBuild lets users upload or generate virus capsid structures and automatically fills in missing elements, applies mutations, and assembles the full 60-unit geometric shell within seconds.

Unified Design Workflow
It unifies previously fragmented processes by providing sequence-to-structure modelling, interactive 3D visualisation, and easy downloading for experiments or publications.

Lower Barriers to Innovation
Ultimately, CapBuild empowers more researchers to explore, design, and innovate in viral vector engineering, advancing gene therapy and vaccine development.

Pricing