ChIPsim

ChIPsim is an R package for the simulation of ChIP-seq data. It is available under the General Public License and comes with absolutely no warranty.

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Download

To install the latest version of ChIPseqR ensure that you are using a recent version of R and execute the following two lines of code within an R session:

source("http://bioconductor.org/biocLite.R")
biocLite("ChIPsim")

Instructions for the installation of R packages can be found on the R Project website for Unix, Windows and Mac OS X.

Documentation

The package documentation is available as PDF.

A tutorial introducing the main functions of ChIPsim and demonstrating its use for the simulation of a nucleosome positioning experiment is available as PDF. This document also includes a discussion of how to extend ChIPsim for use with different types of experiments.

Data

Sequencing data from a simulated ChIP-seq experiment of nucleosome positioning in Arabidopsis is available (read sequences, fastq file, 223 MB; read positions, text file, 70 MB and underlying feature sequence, R data file). The TAIR 8 assembly of the Arabidopsis genome was used to generate read sequences.

Contact

For questions, comments and bug reports please contact Peter Humburg.