home » ChIPsim

ChIPsim

ChIPsim is an R package for the simulation of ChIP-seq data. It is available under the General Public License and comes with absolutely no warranty.

News

2 November 2009
Bioconductor 2.5 has been released. It includes the latest version of ChIPsim.
13 September 2009
ChIPsim is now available as part of Bioconductor.
6 September 2009
Improvements to documentation.
30 August 2009
Minor update to fix specification of imported packages.
28 July 2009
Initial release

Download

To install the latest version of ChIPseqR ensure that you are using a recent version of R and execute the following two lines of code within an R session:

source("http://bioconductor.org/biocLite.R")
biocLite("ChIPsim")

Previous versions can be found in the archive.

Instructions for the installation of R packages can be found on the R Project website for Unix, Windows and Mac OS X.

Documentation

The package documentation is available as PDF and HTML.
A tutorial introducing the main functions of ChIPsim and demonstrating its use for the simulation of a nucleosome positioning experiment is available as PDF. This document also includes a discussion of how to extend ChIPsim for use with different types of experiments.

Data

Sequencing data from a simulated ChIP-seq experiment of nucleosome positioning in Arabidopsis is available (read sequences (fastq file, 223 MB), read positions (text file, 70 MB) and underlying feature sequence (R data file)). The TAIR 8 assembly of the Arabidopsis genome was used to generate read sequences.

Contact

For questions, comments and bug reports please contact Peter.Humburg@csiro.au.